孕期增重过度对子代健康影响的研究进展

孕期增重过度对子代健康影响的研究进展1.内蒙古医科大学研究生院,内蒙古 呼和浩特 010107;
2.内蒙古自治区妇幼保健院,内蒙古 呼和浩特 010020Effects of excessive weight gain during pregnancy on offspring health: a reviewJI Wenhui1,2, CHANG Jinke1, LI Tao11. Graduate School of Inner Mongolia Medical University, Hohhot, Inner Mongolia 010107, China;
2. Maternal and Child Health Hospital of Inner Mongolia Autonomous Region, Hohhot, Inner Mongolia 010020, China 摘要参考文献 相关文章Metrics 摘要 孕期增重过度已经成为严重影响产妇健康的全球性临床及公共卫生问题。孕期增重过度不仅会增加剖宫产率,引起不良妊娠结局,还可影响子代发育和健康。本文对孕期增重过度对子代健康的影响及机制进行综述,发现孕期增重过度增加子代罹患肥胖、心血管疾病、呼吸道感染疾病、糖尿病、多囊卵巢综合征和心理疾病的风险;病理生理学机制包括炎症反应、肠道菌群失调和表观遗传学等,但尚需更多的研究证实。今后研究需进一步探讨孕期不同阶段增重过度对子代健康的影响,为合理控制孕期增重和促进子代健康提供依据。服务把本文推荐给朋友加入引用管理器 E-mail AlertRSS作者相关文章冀文慧 常进科 李弢关键词 ：孕期增重过度, 宫内环境不良, 子代健康   Abstract：Excessive gestational weight gain has already become a global clinical and public health problem that seriously affects maternal health. Excessive gestational weight gain not only increases the cesarean section rate and induces adverse pregnant outcomes, but also affects offspring development and health. This article reviews the effects of excessive weight gain during pregnancy on offspring health and its underlying mechanisms. Excessive gestational weight gain may increase the risk of obesity, cardiovascular diseases, infectious diseases of the respiratory tract, diabetes, polycystic ovary syndrome, mental or psychological illness among offspring, and the pathophysiological mechanisms include inflammatory response, intestinal flora dysbiosis and epigenetics theory. However, further studies are required to validate these hypotheses and to evaluate the effect of excessive weight gain at different gestational stages on offspring health, so as to provide insights into reasonable management of weight gain during pregnancy and improvements of offspring health.Key words：excessive gestational weight gain  poor intrauterine environment  offspring health收稿日期: 2023-05-10     修回日期: 2023-07-16     出版日期: 2023-09-10基金资助:内蒙古自治区卫生健康科技计划项目（202202093）通信作者:李弢,E-mail：1587966757@qq.com   作者简介: 冀文慧,硕士研究生在读

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