减重代谢手术后神经影像改变与认知功能评估的研究进展

肥胖是一种慢性代谢性疾病，表现为体重增长和体内脂肪的过度贮存，这种不平衡的能量代谢紊乱会造成大脑结构和功能发生改变，而与认知相关的大脑区域改变会增加发生认知障碍的风险。减重代谢手术（BMS）作为治疗肥胖和改善肥胖相关合并症的有效手段，术后脑区结构与认知功能明显改善。本文综述了BMS术后认知功能改变的神经影像学基础和认知功能评估的最新进展，讨论了BMS术后脑区结构改变对认知功能的影响，旨在为进一步探索术后认知功能改变机制研究提供参考。

Obesity is a chronic metabolic disease manifested by weight gain and excessive storage of body fat. This imbalanced energy metabolism disorder causes changes in brain structure and function, while changes in brain regions associated with cognition increase the risk of cognitive impairment. Bariatric metabolic surgery (BMS) is an effective means to treat obesity and improve obesity-related complications, and the structure and cognitive function of brain regions are significantly improved after surgery. This article reviews the latest progress in the neuroimaging basis of cognitive function changes and cognitive function assessment after BMS. It discusses the impact of postoperative brain area structure changes on cognitive function, aiming to provide a reference for further exploring the mechanism of postoperative cognitive function changes.

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